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Author Archives: Yoko Nagai

VarySysDB Disease Edition (VaDE) version 1.2 was released.

June 26th, 2014 | Posted by Yoko Nagai in Uncategorized - (Comments Off on VarySysDB Disease Edition (VaDE) version 1.2 was released.)

We released VarySysDB Disease Edition (VaDE) version 1.2.

  • New URL is http://bmi-tokai.jp/VaDE/.
  • Released genome browser and supported Japanese language.
  • Data update: Add association data of hypertention and rheumatoid arthritis that is manually curated by our team.
  • Enhancements: Enhanced record click function to show detail information, search system, categorized trait search system, and inner-links.
  • Bug fixes: Fixed outer-link URL.

A New Database of “Reproducible” Disease-Associated Genomic Polymorphisms Launched

April 24th, 2014 | Posted by Yoko Nagai in News - (Comments Off on A New Database of “Reproducible” Disease-Associated Genomic Polymorphisms Launched)

We developed a new database of genomic polymorphisms that are “reproducibly” associated with disease risks, drug responses and other traits by comprehensively extracting information from many scientific papers, and released it as “VarySysDB Disease Edition (VaDE)”. The VaDE database contains detailed information of disease-associated genomic polymorphisms that have been confirmed by multiple, independent studies for each human population. For example, users can search, show and download all the disease-associated genomic polymorphisms that are reproduced in the East Asian population. VaDE also provides functional information and linkage disequilibria of the polymorphic genomic sites. While genomic polymorphisms are being widely used in researches for predicting disease risks, our database can provide reliable sets of disease-associated genomic polymorphisms with the firm evidence.

The VaDE database is accessible temporarily from here. Your feedback is highly appreciated and will help us to improve our database in the future.

This database project is partially supported by JSPS KAKENHI, Grant-in-Aid for Publication of Scientific Research Results (Grant Numbers 258055 and 268046) in 2013-2014.